Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition

Figure 8

(a) Modelling of HS in rat tails. (b) Representative macroscopic photographic images of HS after being treated with topical medication at 0, 7, 14, 21, and 28 days (scale bars = 5 mm). (c) Mature hypertrophic scars and normal skin tissues of rat tails harvested from the four groups (the HS model group, the silicone group, the DSO group, and DSO + silicone group). Significant differences between different groups or any other groups vs the model group are expressed as , , and , while significant differences between any other group and the control group are expressed as ^# = , ^## = , and ^### = .

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