[Retracted] Study on the Relationship between MMP-2, MMP-9 Gene Polymorphisms, and the Risk of Colorectal Cancer

Table 2

Comparison of MMP-2 and MMP-9 genotype and frequency distribution between the colorectal cancer group and control group.

Indexes	Genetic locus			Colorectal cancer group (n = 308)		Control group (n = 300)		χ^2
				Number of cases	Frequency (%)	Number of cases	Frequency (%)
MMP-2	Genotype	−1306 (C/T)	CC	243	78.90	226	75.33	1.385	0.500
			CT	62	20.13	69	23.00
			TT	3	0.97	5	1.67
		−735 (C/T)	CC	206	66.88	167	55.67	9.026	0.011
			CT	86	27.92	118	39.33
			TT	16	5.19	15	5.00
		−790 (T/G)	TT	235	76.30	226	75.33	0.182	0.913
			TG	69	22.40	69	23.00
			GG	4	1.30	5	1.67
	Gene frequencies	−1306 (C/T)	C	548	88.96	521	86.83	1.295	0.255
			T	68	11.04	79	13.17
		−735 (C/T)	C	498	80.84	452	75.33	5.401	0.020
			T	118	19.16	148	24.67
		−790 (T/G)	T	539	87.50	521	86.83	0.121	0.728
			G	77	12.50	79	13.17
MMP-9	Genotype	−1562 (C/T)	CC	169	54.87	205	68.33	13.764	0.001
			CT	124	40.26	90	30.00
			TT	15	4.87	5	1.67
		R668Q	RR	291	94.48	276	92.00	1.528	0.466
			RQ	13	4.22	19	6.33
			QQ	4	1.30	5	1.67
		P574R	PP	275	89.29	277	92.33	1.809	0.405
			PR	26	8.44	19	6.33
			RR	7	2.27	4	1.33
	Gene frequencies	−1562 (C/T)	C	452	73.38	500	83.33	13.871	<0.001
			T	154	25.00	100	16.67
		R668Q	R	595	96.59	571	95.17	1.564	0.211
			Q	21	3.41	29	4.83
		P574R	P	576	93.51	573	95.50	2.320	0.128
			R	40	6.49	27	4.50