Compatibility of Niuhuang Jiedu Tablets Results in Attenuated Arsenic Bioaccumulation and Consequent Protection against Realgar-Induced Toxicity in Mice

Figure 2

The summary of pathway analysis in the serum of realgar-exposed mice compared with control mice. Each circle represents one metabolic pathway; the size of circle shows the positive correlation with the impact of each pathway; the colour of circle denotes the significance from the highest value in red to the lowest value in white. (1) Valine, leucine, and isoleucine biosynthesis; (2) synthesis and degradation of ketone bodies; (3) glyoxylate and dicarboxylate metabolism; (4) pyruvate metabolism; (5) citrate cycle; (6) glycolysis or gluconeogenesis; (7) butanoate metabolism.