Research Article

Sonchus oleraceus L. Promotes Gastroprotection in Rodents via Antioxidant, Anti-Inflammatory, and Antisecretory Activities

Table 3

Effects of HES on gastric acid secretion.


Vehicle7.54 ± 0.650.0360 ± 0.00661.92 ± 0.266.47 ± 0.70
Omeprazole6.62 ± 0.800.0092 ± 0.0040a5.84 ± 1.11a4.08 ± 0.18a
HES7.58 ± 0.890.0137 ± 0.0045a5.53 ± 0.99a2.35 ± 0.57b

Note. Vehicle (0, 1 mg/kg), omeprazole (20 mg/kg), HES (300 mg/kg); volume (mL); total acidity (Eq [H+]/mL); peptic activity (mmol of tyrosine/mL). Values are expressed as means ± S.E.M (n = 5–6). One-way ANOVA followed by Bonferroni’s test. a and b vs vehicle-treated group.