Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway

Table 1

Animal groups and drug administration.

Group	Treatment	Drug administration (i.g.)
Control	ordinary rodent chow	Normal saline
Model	high-fat diet	Normal saline
Simvastatin (simva)	high-fat diet	Simvastatin (5 mg/kg/d)
Astragali radix (AR)	high-fat diet	Astragali radix (3.9 g/kg/d)
Coptis rhizoma (CR)	high-fat diet	Coptis rhizoma (1.3 g/kg/d)
Astragali radix–Coptis rhizoma (ARCR)	high-fat diet	ARCR (5.2 g/kg/d)
ARCR + AS1517499	high-fat diet and AS1517499 (i.p.)	ARCR (5.2 g/kg/d)

Note: i.g.: intragastric administration; i.p.: intraperitoneal administration.