Molecular Characterization of Gene-Mediated Resistance and Susceptibility of ESKAPE Clinical Isolates to Cistus monspeliensis L. and Cistus salviifolius L. Extracts

Table 5

Phytochemical composition of ethyl acetate and n-butanol fractions from two Cistus species.

Identified compound	Area (%)
	C. monspeliensis		C. salviifolius
	Ethyl acetate	n-butanol	Ethyl acetate	n-butanol
Monoterpene hydrocarbons	21.15	20.23	3.8	16.93
α-Pinene	2.26	2.74	0.36	1.97
β-Pinene	1.85	—	—	—
β-Myrcene	1.06	8.22	1.46	1.28
Camphene	1.36	1.37	0.21	1.01
α-Phellandrene	6.70	3.24	—	5.97
Limonene	7.92	4.66	1.77	6.70
Monoterpenes oxygenated	1.64	2.26		5.4
Eucalyptol (1,8-cineol)	1.64	2.26	—	1.84
Sesquiterpenes hydrocarbons	3.89
Cedrene	3.89	—	—	—
Sesquiterpenes oxygenated	61.41	5.34	70.77	9.41
Viridiflorol	59.84	—	70.77	6.92
Elemol	—	5.43	—	—
Agarospirol	—	—	—	2.49
2,6-Di-tert-butyl-p-cresol	1.57	—	—	—
Phenolic compounds	1.01	5.77		5
2,4-Bis(1,1-dimethylethyl)-phenol	1.01	5.77	—	5.00
Nonterpene compounds	10.9	66.31	3.90	63.26
Hydrocarbons		36.81		44.75
7,9-Dimethyl-hexadecane	—	6.72	—	7.59
5,7-Dimethyl-undecane	—	1.39	—	3.65
8-Hexyl-pentadecane	—	—	—	6.51
5-(2-Methylpropyl)-nonane	—	2.18	—	—
2-Methyl-eicosane	—	2.24	—	—
2,6,10,15-Tetramethyl-heptadecane	—	—	—	2.94
8-Methyl-heptadecane	—	—	—	8.08
10-Methyl-eicosane	—	6.00	—	4.61
7-Hexyl-eicosane	—	—	—	1.77
Eicosane	—	1.46	—	1.51
2,6,11,15-Tetramethyl-hexadecane	—	5.76	—	—
2,4-Dimethyl-undecane	—	5.61	—	—
2,6,10,14,18-Pentamethyl-eicosane	—	5.45	—	8.09
Alcohols	2.73	6.74		4.48
2-(2-Hydroxypropoxy)-1-propanol	2.73	—	—	2.00
2-Isopropyl-5-methyl-1-heptanol	—	2.02	—	—
2-Ethyl-2-methyl-tridecanol	—	4.72	—	2.48
Carboxylic acids	4.33		3.90
4-Acetyl benzoic acid	4.33	—	3.90	—
Fatty acids	1.22
Pelargonic acid	1.22	—	—	—
Alkanes	2.62
1,1′-Oxybis-2-propanol	2.62	—	—	—
1,1-Dibutoxy-butane	—	—	—	3.56
Ketones		2.17		0.87
2-Heptyl-4-methyl-1,3-dioxane	—	2.17	—	0.87
Ester		9.39		13.16
Butyl butyrate	—	9.39	—	13.16
Ether		3.83
Butane, 1,1-dibutoxy-Heptadecane, 8-methyl-	—	3.83	—	—
Unknown	—	7.37	—	—