Molecular Characterization of Gene-Mediated Resistance and Susceptibility of ESKAPE Clinical Isolates to Cistus monspeliensis L. and Cistus salviifolius L. Extracts
Table 7
Determination of IZD (mm), MIC, and MBC (mg/mL) of C. monspeliensis extracts.
Strains
E. faecium
S. aureus
K. pneumoniae
A. baumannii
P. aeruginosa
E. cloacae
Extracts
IZD mm
MIC mg/mL
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
CMM
17
0.42
0.85
2
20
0.01
0.42
32
12
1.75
6.87
4
15
0.10
3.43
32
12
0.21
6.87
33
14
0.85
27.5
32
CMS
13
0.42
0.42
1
14
0.05
0.85
16
9
13.75
13.75
1
12
0.42
0.42
1
10
0.42
6.87
6
10
3.43
13.75
4
F1MM
11
0.42
1.71
4
10
0.01
0.05
4
10
6.87
13.75
2
9
3.43
3.43
1
10
3.42
13.75
4
8
3.43
6.87
2
F1MS
10
0.42
0.42
1
10
0.01
1.71
131
9
6.87
13.75
2
8
3.43
6.87
2
10
3.43
13.75
4
8
6.87
13.75
2
F2MM
11
0.10
0.42
4
11
0.01
0.10
8
10
3.43
6.87
2
10
3.43
6.87
2
9
1.71
6.87
4
10
3.43
13.75
4
F2MS
10
0.21
1.71
8
10
0.02
0.85
32
9
6.87
6.87
1
6
3.43
6.87
2
7
3.43
6.87
2
9
3.43
27.5
8
F3MM
17
0.85
1.71
2
17
0.01
0.10
8
13
0.42
6.87
16
15
0.85
3.43
4
15
0.02
6.87
33
14
3.43
13.75
4
F3MS
14
0.42
0.42
1
13
0.01
0.85
65
10
3.43
6.87
2
13
0.05
0.85
16
13
0.02
3.43
131
11
3.43
13.75
4
F4MM
14
0.85
6.87
8
13
0.01
0.85
65
9
0.85
13.75
16
10
1.71
6.87
4
11
3.43
6.87
2
10
6.87
27.5
2
F4MS
11
0.85
0.85
1
10
0.10
3.43
32
7
0.85
6.87
8
7
1.71
3.43
2
9
6.87
6.87
1
8
6.87
27.5
2
F5MM
13
0.85
1.71
2
13
0.05
0.85
16
11
3.43
6.87
2
10
1.71
6.87
4
12
0.10
6.87
64
10
6.87
13.75
2
F5MS
11
0.85
1.71
2
10
0.21
1.71
8
8
6.87
13.75
2
7
3.43
3.43
1
6
1.71
6.87
4
8
6.87
27.5
4
CCMM: crude CM from maceration; CCMS: crude CM from Soxhlet; F1CMM: hexane fraction of CM from maceration; F1CMS: hexane fraction of CM from Soxhlet; F2CMM: dichloromethane fraction of CM from maceration; F2CMS: dichloromethane fraction of CM from Soxhlet; F3CMM: ethyl acetate fraction of CM from maceration; F3CMS: ethyl acetate fraction of CM from Soxhlet; F4CMM: n-butanol fraction of CM from maceration; F4CMS: n-butanol fraction of CM from Soxhlet; F5CMM: remaining aqueous of CM from maceration; F5CMS: remaining aqueous of CM from Soxhlet.
