Molecular Characterization of Gene-Mediated Resistance and Susceptibility of ESKAPE Clinical Isolates to Cistus monspeliensis L. and Cistus salviifolius L. Extracts
Table 8
Determination of IZD (mm), MIC, and MBC (mg/mL) of C. salviifolius extracts.
Strains
E. faecium
S. aureus
K. pneumoniae
A. baumannii
P. aeruginosa
E. cloacae
Extracts
IZD mm
MIC mg/Ml
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
IZD
MIC
MBC
MBC/MIC
CSM
15
0.21
1.71
8
16
0.10
0.42
4
7
3.43
13.75
4
8
0.85
3.43
4
9
0.05
3.43
64
8
1.71
13.75
8
CSS
13
0.42
0.42
1
14
0.10
3.43
32
6
6.87
6.87
1
6
0.21
1.71
8
7
0.10
6.87
64
6
3.43
6.87
2
F1SM
10
3.43
6.87
2
12
0.01
0.85
65
8
6.87
13.75
2
7
3.43
6.87
2
8
0.85
13.75
16
9
6.87
6.87
1
F1SS
10
0.42
1.71
4
12
0.10
3.43
32
8
6.87
13.75
2
6
3.43
6.87
2
7
0.05
13.75
259
8
3.43
13.75
4
F2SM
13
1.87
6.87
4
14
0.01
0.21
16
9
3.43
27.5
8
8
1.71
3.43
2
8
1.71
6.87
4
9
3.43
13.75
4
F2SS
11
3.43
6.87
2
12
0.85
6.87
8
7
13.75
13.75
1
6
3.43
3.43
1
7
3.43
13.75
4
7
3.43
27.5
8
F3SM
14
0.42
0.85
2
14
0.01
0.05
4
12
0.42
6.87
16
12
3.43
3.43
1
13
1.71
3.43
2
12
3.43
6.87
2
F3SS
12
0.21
0.21
1
12
0.10
3.43
32
9
3.43
6.87
2
6
1.71
1.71
1
13
3.43
3.43
1
9
6.87
13.75
2
F4SM
14
0.42
0.85
2
15
0.01
0.21
16
10
0.42
6.87
16
12
0.85
3.43
4
13
0.05
6.87
129
10
6.87
13.75
2
F4SS
11
1.71
3.43
2
12
0.26
6.87
26
8
6.87
6.87
1
6
1.71
3.43
2
9
3.43
13.75
4
7
6.87
27.5
4
F5SM
15
0.85
1.71
2
16
0.05
0.21
4
11
3.43
6.87
2
13
1.71
6.87
4
15
0.02
6.87
264
10
6.87
13.75
2
F5SS
11
6.87
6.87
1
12
3.43
13.75
4
8
6.87
6.87
1
6
1.71
1.71
1
12
3.43
13.75
4
7
6.87
27.5
2
CCSM: crude CS from maceration; CCSS: crude CS from Soxhlet; F1CSM: hexane fraction of CS from maceration; F1CSS: hexane fraction of CS from Soxhlet; F2CSM: dichloromethane fraction of CS from maceration; F2CSS: dichloromethane fraction of CS from Soxhlet; F3CSM: ethyl acetate fraction of CS from maceration; F3CSS: ethyl acetate fraction of CS from Soxhlet; F4CSM: n-butanol fraction of CS from maceration; F4CSS: n-butanol fraction of CS from Soxhlet; F5CSM: remaining aqueous fraction of CS from maceration; and F5CSS: remaining aqueous fraction of CS from Soxhlet.
