Evidence-Based Complementary and Alternative Medicine

Review Article

Clinical Evidence and Potential Mechanisms of Complementary Treatment of Ling Gui Zhu Gan Formula for the Management of Serum Lipids and Obesity

Table 2

The original data of outcome indicators.

Included studies (authors, year

TC (Mm)

TG (Mm)

LDL-c (Mm)

HDL-c (Mm)

BMI (kg/m²)

BW (kg)

WC (cm)

Baseline

After intervention

Baseline

After intervention

Baseline

After intervention

Baseline

After intervention

Baseline

After intervention

Baseline

After intervention

Baseline

After intervention

Chen (2012)

T:4.81 ± 1.17

T:3.19 ± 1.03

T:3.08 ± 1.22

T:1.41 ± 0.69

T:3.76 ± 0.91

T:2.79 ± 0.69

T:1.09 ± 0.35

T:1.56 ± 0.39

T:25.06 ± 1.42

C:4.86 ± 1.27

C:3.68 ± 1.13

C:3.06 ± 1.13

C:1.89 ± 0.78

C:3.91 ± 0.66

C:2.67 ± 0.57

C:1.19 ± 0.41

C:1.15 ± 0.41

C:25.15 ± 1.52

Du et al. (2019)

T:7.42 ± 0.76

T:3.81 ± 0.42

T:3.84 ± 0.41

T:1.26 ± 0.16

T:1.03 ± 0.12

T:1.14 ± 0.29

C:7.28 ± 0.81

C:7.36 ± 0.81

C:3.72 ± 0.39

C:1.98 ± 0.23

C:1.01 ± 0.13

C:1.05 ± 0.11

Han and Zhang (2016)

T:5.19 ± 0.98

T:4.23 ± 1.04

T:2.50 ± 0.66

T:2.08 ± 0.38

T:3.09 ± 0.76

T:2.59 ± 0.45

T:0.97 ± 0.42

T:1.26 ± 0.21

C:5.21 ± 1.32

C:4.77 ± 1.29

C:2.53 ± 0.58

C:2.30 ± 0.47

C:3.12 ± 0.85

C:2.66 ± 0.32

C:0.98 ± 0.18

C:1.21 ± 0.22

Huang (2016)

T:5.53 ± 0.91

T:4.60 ± 0.85

T:1.55 ± 0.89

T:1.46 ± 0.78

T:27.91 ± 2.64

T:23.68 ± 2.19

C:5.36 ± 0.85

C:5.12 ± 0.91

C:1.56 ± 0.96

C:1.51 ± 0.92

C:27.88 ± 2.94

C:25.96 ± 2.31

Huang et al. (2017)

T:5.63 ± 1.33

T:5.04 ± 1.07

T:2.77 ± 0.92

T:1.96 ± 0.54

T:3.89 ± 1.08

T:2.69 ± 1.62

T:1.36 ± 0.34

T:1.78 ± 0.65

T:31.14 ± 3.57

T:27.88 ± 2.34

T:81.25 ± 6.31

T:75.82 ± 5.94

C:5.45 ± 1.54

C:5.31 ± 1.63

C:2.84 ± 0.79

C:2.21 ± 0.86

C:3.77 ± 1.25

C:3.14 ± 1.51

C:1.42 ± 0.38

C:1.55 ± 0.43

C:30.51 ± 3.09

C:28.26 ± 3.83

C:81.16 ± 5.67

C:79.07 ± 4.69

Jiang et al. (2018)

T:5.89 ± 0.82

T:4.71 ± 0.77

T:1.84 ± 0.33

T:1.46 ± 0.27

T:3.54 ± 0.64

T:2.28 ± 0.55

T:1.11 ± 0.25

T:1.92 ± 0.26

C:5.76 ± 0.85

C:5.05 ± 0.78

C:1.83 ± 0.32

C:1.57 ± 0.26

C:3.56 ± 0.53

C:2.66 ± 0.53

C:1.10 ± 0.21

C:1.74 ± 0.26

Ke et al. (2012a)

T:6.08 ± 0.88

T:5.62 ± 0.41

T:3.49 ± 2.55

T:2.41 ± 1.14

T:3.78 ± 1.06

T:2.78 ± 0.51

T:1.13 ± 0.27

T:1.22 ± 0.45

T:27.5 ± 2.0

T:25.0 ± 1.3

T:78.0 ± 9.9

T:70.5 ± 4.5

T:91.21 ± 7.07

T:81.76 ± 3.39

C:6.12 ± 0.86

C:5.73 ± 0.58

C:3.41 ± 2.53

C:2.64 ± 1.61

C:3.65 ± 1.08

C:2.83 ± 0.74

C:1.14 ± 0.29

C:1.19 ± 0.31

C:28.5 ± 3.6

C:26.7 ± 2.4

C:76.8 ± 9.6

C:72.6 ± 6.7

C:91.37 ± 7.16

C:86.94 ± 5.00

Qiu and Rong (2004)

T:6.25 ± 0.52

T:5.28 ± 0.44

T:2.64 ± 0.35

T:1.55 ± 0.25

C:6.18 ± 0.47

C:5.26 ± 0.61

C:2.58 ± 0.42

C:1.50 ± 0.24

Shen et al. (2020)

T:6.14 ± 0.63

T:4.58 ± 0.82

T:3.46 ± 1.25

T:2.24 ± 0.98

T:27.21 ± 3.15

T:23.03 ± 2.86

C:6.25 ± 0.57

C:5.48 ± 0.72

C:3.52 ± 1.18

C:2.81 ± 1.14

C:27.53 ± 2.96

C:25.07 ± 3.32

Song and Li (2013)

T:4.70 ± 0.69

T:3.11 ± 0.53

T:2.21 ± 0.88

T:1.12 ± 0.51

C:4.58 ± 0.72

C:3.96 ± 0.76

C:2.09 ± 0.76

C:1.93 ± 0.47

Wang et al. (2017)

T:5.37 ± 1.09

T:4.76 ± 0.84

T:1.65 ± 0.43

T:1.28 ± 0.31

T:3.10 ± 0.64

T:2.71 ± 0.53

T:1.26 ± 0.31

T:1.49 ± 0.25

T:31.92 ± 1.83

T:27.69 ± 2.36

C:5.29 ± 1.13

C:5.23 ± 1.20

C:1.59 ± 0.47

C:1.54 ± 0.36

C:3.09 ± 0.70

C:3.01 ± 0.68

C:1.29 ± 0.30

C:1.31 ± 0.32

C:31.53 ± 1.64

C:31.07 ± 1.85

Wen (2020)

T:4.68 ± 0.62

T:3.10 ± 0.51

T:2.18 ± 0.87

T:1.09 ± 0.46

C:4.70 ± 0.66

C:3.95 ± 0.57

C:2.13 ± 0.81

C:1.81 ± 0.53

Xia et al. (2017)

T:6.37 ± 0.82

T:4.26 ± 0.75

T:2.23 ± 0.62

T: 1.57 ± 0.58

T:4.19 ± 0.74

T:2.32 ± 0.54

T:1.26 ± 0.35

T:1.55 ± 0.40

T:23.3 ± 2.7

C:6.44 ± 0.75

C:5.32 ± 0.82

C:2.29 ± 0.55

C:1.86 ± 0.53

C:4.12 ± 0.65

C:2.95 ± 0.76

C:1.22 ± 0.42

C:1.28 ± 0.36

C:22.8 ± 2.2

Zhao (2020)

T:6.36 ± 0.83

T:4.25 ± 0.76

T:2.22 ± 0.63

T:1.56 ± 0.59

T:4.18 ± 0.75

T:2.31 ± 0.55

T:1.25 ± 0.34

T:1.54 ± 0.41

C:6.43 ± 0.76

C:5.31 ± 0.83

C:2.28 ± 0.56

C:1.85 ± 0.54

C:4.11 ± 0.66

C:2.94 ± 0.77

C:1.21 ± 0.43

C:1.27 ± 0.37

Zhou et al. (2015)

T:6.58 ± 1.10

T:5.04 ± 0.52

T:3.10 ± 0.72

T:1.68 ± 0.58

T:2.30 ± 0.43

T:1.03 ± 0.35

T:0.67 ± 0.13

T:1.47 ± 0.34

C:6.30 ± 1.02

C:5.14 ± 0.54

C:3.12 ± 0.72

C:1.65 ± 0.5

C:2.30 ± 0.51

C:1.04 ± 0.32

C:0.70 ± 0.15

C:1.55 ± 0.14