Exploring the Protective Effect and Mechanism of Buddlejae Flos on Sodium Selenite-Induced Cataract in Rats by Network Pharmacology, Molecular Docking, and Experimental Validation

Figure 4

(a) Binding mode of luteolin with AKT1, TP53, CASP3, EGFR, and TNF. (b) Binding mode of apigenin with AKT1, TP53, CASP3, EGFR, and TNF. (c) Binding mode of acacetin with AKT1, TP53, CASP3, EGFR, and TNF. The protein’s backbone was rendered in a tube and coloured in bright blue. Compounds are rendered by yellow. A, B, C, D, and E represent AKT1, TP53, CASP3, EGFR, and TNF, respectively. The yellow dash indicates the hydrogen bond distance or π-stacking distance.

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