Piperine Enhances the Antimalarial Activity of Curcumin in Plasmodium berghei ANKA-Infected Mice: A Novel Approach for Malaria Prophylaxis

Figure 5

(a) Relative parasitic load and (b) quantification of the percentage CD68-positive area after curcumin and piperine administration in P. berghei ANKA-infected mice (n = 2 per group). The data are presented as mean ± SEM. ; ; and . ART, artesunate 5 mg/kg BW; CUR, curcumin 300 mg/kg BW; CUR + PIP, curcumin 300 mg/kg BW and piperine 20 mg/kg BW; PIP, piperine 20 mg/kg BW.

(a)

(b)