The Potential Hepatoprotective Effect of Paeoniae Radix Alba in Thioacetamide-Induced Acute Liver Injury in Rats

Figure 2

Paeoniae Radix Alba activated p-LKB1/AMP-activated protein kinase/Sirtuin 1. Paeoniae Radix Alba significantly elevated the protein expression of p-LKB1, p-AMP-activated protein kinase, and Sirtuin 1. Data are mean ± standard error of the mean (n = 7). , , and versus the normal group and ^∗, ^∗∗, and ^∗∗∗ versus the thioacetamide control group. AMPK: AMP-activated protein kinase; normal: received distilled water only; control: thioacetamide-induced acute liver injury treated with distilled water; silymarin: thioacetamide-induced acute liver injury treated with silymarin (100 mg/kg); PR100: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (100 mg/kg); and PR200: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (200 mg/kg).