The Potential Hepatoprotective Effect of Paeoniae Radix Alba in Thioacetamide-Induced Acute Liver Injury in Rats

Figure 6

Paeoniae Radix Alba alleviated histological alterations in the liver. Representative hematoxylin and eosin staining of thioacetamide-induced acute liver injury. Injury was notably ameliorated by the administration of Paeoniae Radix Alba. Scale bar = 100 μm (magnification, ×200). Blue arrows indicate inflammatory cell infiltrations on H&E sections. Black arrows indicate apoptotic body. Histological analysis was measured using ImageJ (NIH). Data are expressed as the mean ± standard error of the mean (n = 7). versus the normal group and ^∗∗ and ^∗∗∗ versus the thioacetamide control group. Normal: received distilled water only; control: thioacetamide-induced acute liver injury treated with distilled water; silymarin: thioacetamide-induced acute liver injury treated with silymarin (100 mg/kg); PR100: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (100 mg/kg); and PR200: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (200 mg/kg).