Research Article

The Potential Hepatoprotective Effect of Paeoniae Radix Alba in Thioacetamide-Induced Acute Liver Injury in Rats

Table 1

Change of body weight, liver weight, and a relative liver weight.

GroupLiver weight (g)Body weight (g)LW/BW ratio (%)

Normal8.3 ± 0.11238.9 ± 2.083.5 ± 0.05
Control10.1 ± 0.21202.9 ± 3.485.0 ± 0.10
Silymarin9.8 ± 0.13202.5 ± 2.534.8 ± 0.06
PR1009.8 ± 0.17200.2 ± 3.064.9 ± 0.08
PR2009.5 ± 0.24197.4 ± 4.094.8 ± 0.11

Data are represented as mean ± standard error of the mean (n = 7). versus the normal group and and versus the thioacetamide control group. LW: liver weight; BW: body weight; normal: received distilled water only; control: thioacetamide-induced acute liver injury treated with distilled water; (3) silymarin: thioacetamide-induced acute liver injury treated with silymarin (100 mg/kg); PR100: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (100 mg/kg); and PR200: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (200 mg/kg).