The Potential Hepatoprotective Effect of Paeoniae Radix Alba in Thioacetamide-Induced Acute Liver Injury in Rats

Table 2

Levels of AST, ALT, and ammonia in serum.

Group	AST (IU/L)	ALT (IU/L)	Ammonia (nmoL/μL)
Normal	26.67 ± 1.39	2.74 ± 0.54	11.62 ± 0.62
Control	58.75 ± 2.75	26.48 ± 2.37	19.18 ± 0.74
Silymarin	50.06 ± 1.98	17.07 ± 2.13	14.73 ± 1.03
PR100	49.01 ± 2.34	14.99 ± 3.65	12.68 ± 0.46
PR200	44.73 ± 2.09	14.50 ± 3.54	11.58 ± 0.73

The higher dose of Paeoniae Radix Alba (200 mg/kg) significantly reduced the levels of AST, ALT, and ammonia. Data are mean ± standard error of the mean (n = 7). versus the normal group and and versus the thioacetamide control group. Normal: received distilled water only; control: thioacetamide-induced acute liver injury treated with distilled water; silymarin: thioacetamide-induced acute liver injury treated with silymarin (100 mg/kg); PR100: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (100 mg/kg); and PR200: thioacetamide-induced acute liver injury treated with Paeoniae Radix Alba (200 mg/kg).