Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System

Figure 22

Representative images of IL-1β, IL-2, and IL-4 immunoreactive cells in the Spleen. In morphine control group, significant decreases of splenic immune stimulatory cytokines-IL-1β, IL-2 and IL-4 immunolabeled cells were demonstrated as compared to normal group, however, these morphine-induced decreases of IL-1β, IL-2, and IL-4 immunoreactivity were obviously and significantly normalized by HT7, SI5, and LI5 acupunctures, in that orders. (a) normal; (b) M 10; (c) M 10 + HT7 acupuncture; (d) M 10 + SI5 acupuncture; (e) M 10 + LI5 acupuncture. All ABC-based immunohistochemistric eosin stain. Scale bars: 80 μm. IL : Interleukin; ABC : Avidin-biotin-peroxidase complex.

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