Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System

Figure 29

Representative images of IL-6, IL-10, and IL-12A immunoreactive cells in the S-LN. In morphine group, significant decreases of S-LN immune stimulatory cytokines-IL-6 and IL-12A immunolabeled cells, and increase of immune suppressive cytokine-IL-10 immunolabeled cells on the S-LN were demonstrated as compared to those of normal, however these morphine-induced decreases of IL-6 and IL-12, and increase of IL-10 immunoreactivity were obviously and significantly normalized by HT7, SI5 and LI5 acupunctures, in that orders. (a) normal; (b) M 10; (c) M 10 + HT7 acupuncture; (d) M 10 + SI5 acupuncture; (e) M 10 + LI5 acupuncture. All ABC based immunohistochemistric eosin stain. Scale bars: 80 μm. S-LN : Submandibular lymph node; IL : Interleukin; ABC : Avidin-biotin-peroxidase complex.

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