Medicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Mentha spicata

Table 9

Antioxidant activity of Mentha spicata.

Parts used	Extracts	Methods used	Key results	References
Whole plant	Methanol extract	DPPH	IC50 = 65.13 ± 1.29 μg/mL	[103]
		ABTS	IC50 = 52.31 ± 0.81 μg/mL
Aerial parts	Ethanol extract	DPPH	IC50 = 87.89 μg/mL	[102]
		ABTS	IC50 = 173.80 μg/mL
Aerial parts	Essential oil	DPPH	IC50 = 3450 ± 172.5 μg/mL	[48]
		ABTS	IC50 = 40.2 ± 0.2 μg/mL
		FRAP	IC50 = 215 ± 4.50 μg/mL
Leaves	Essential oil	DPPH	IC50 = 9544.6 ± 196.2 μg/mL	[65]
		ABTS	IC50 = 36.2 ± 3.2 μg/mL
		Reducing power	RP50 = 452.3 ± 0.4 μg/mL
		Phosphomolybdate	RP50 = 53.3 ± 2.8 μg/mL
Leaves	Essential oil	DPPH	IC50 = 10 ± 0.24 μg/mL	[104]
		Superoxide anion	IC50 = 1.33 ± 0.10 μg/mL
Aerial parts	Ethanol-water extract	DPPH	IC50 = 105.8 ± 3.98 μg/mL	[9]
		Nitric oxide radical scavenger	IC50 = 210.6 ± 7.7 μg/mL
		Metal chelating	IC50 = 757.4 ± 29.5 μg/mL
		Scavenging of H2O2	IC50 = 631.1 ± 26.0 μg/mL
Seeds	Methanol extract	DPPH	Inhibition = 89.91 ± 2.12%	[33]
Leaves	Ethanol extract	DPPH	IC50 = 16.2 ± 0.2 μg/mL	[105]
		ABTS	IC50 = 10.3 ± 0.9 μg/mL
		TEAC	TEAC = 0.90 ± 0.07 mM
Leaves	Essential oils	DPPH	IC50 = 8.81 μL/mL	[78]
Leaves	Essential oils	DPPH	IC50 = 41,23 μL/mL	[80]
Aerial parts	Essential oils	DPPH	IC50 = 13.3 ± 0.6 μL/mL	[5]
	Essential oil	DPPH	IC50 = 72.07 ± 0.34 mg/mL	[11]
Aerial parts	Water extract	DPPH	Inhibition = 74.2 ± 0.2%	[106]
		β-Carotene	Inhibition = 79.1 ± 2.4%
Leaves	Water extract	DPPH	EC50 = 336 ± 3 μg/mL	[107]
		Reducing power	EC50 = 198 ± 2 μg/mL
		TBARS	EC50 = 152 ± 5 μg/mL
Leaves	Essential oil	DPPH	IC50 = 21.19 ± 7.17 μg/mL	[82]
		Reducing power	IC50 = 2.28 ± 0.68 μg/mL
		DPPH	Inhibition = 30.52 ± 0.09% at a concentration of 10 μg/mL
Aerial parts	Essential oil	DPPH	IC50 = 3.08 ± 0.07 μg/mL	[108]
		Reducing power	EC50 = 2.49 ± 0.07 μg/mL
		Chelating power	IC50 = 6.33 ± 0.12 μg/mL
		β-Carotene	IC50 = 6.4 ± 0.07 μg/mL
Leaves	Essential oil	β-Carotene-linoleic acid	Antioxidant activity = 25.37% at 500 μg/mL	[44]
		DPPH	Antioxidant activity = 13.81% at 500 μg/mL
Aerial parts	Ethanol extract	DPPH	Radical scavenging effect = 18.34 ± 2.2% at a concentration of 0.4 mg/mL	[50]
	Essential oil	DPPH	IC50 ˃ 2.5 μg/mL	[87]
Leaves	Essential oil	DPPH	IC50 = 80.45 ± 1.86 μg/mL	[86]
		FRAP	IC50 = 101.78 ± 3.14 μg/mL
		ABTS	IC50 = 139.59 ± 3.12 μg/mL
Leaves	Essential oil	ABTS	IC50 = 195.1 ± 4.2 mg/L	[72]
		DPPH	IC50 = 3476.3 ± 133 mg/L