Research Article

Hypoglycemic, Hypolipidemic, and Anti-Inflammatory Effects of Beta-Pinene in Diabetic Rats

Table 1

Evaluation of biochemical parameters in rat sera after oral (v.o.) treatment with β-pinene for 7 days.

ParametersVehicle
Glib (5 mg/kg, v.o.)Beta-pinene (mg/kg, v.o.)
2550100

Glucose (mg/dL)334.1 ± 27.23
77.57 ± 21
(76.7%)
393.9 ± 12.21
126.3 ± 18.62
(62.2%)
140.4 ± 27.25
(57.9%)
CT (mg/dL)88.07 ± 8.791
65.88 ± 5.721
78.82 ± 6.616
86.57 ± 5.694
82.17 ± 11.2
HDL (mg/dL)182.6 ± 8.049
26.79 ± 6.284
(85.3%)
178.5 ± 18.68
64.57 ± 3.867
(64.6%)
46 ± 7.326
(74.8%)
LDL (mg/dL)64.57 ± 3.867
12.93 ± 1.902
(79.9%)
58 ± 7.849
15.69 ± 2.948
(75.7%)
14.9 ± 2.241
(76.9%)
VLDL (mg/dL)112.5 ± 17.31
14.72 ± 1.224
(86.9%)
85.82 ± 7.535
(23.7%)
15.92 ± 2.54
(85.8%)
17.08 ± 0.8871
(84.8%)
TG (mg/dL)354 ± 22.88 —65.88 ± 5.721
(81.3%)
422 ± 33.73 —168.4 ± 26.02
(52.7%)
145.6 ± 23.96
(58.8%)
AST (UI/L)88.68 ± 2.88
52.4 ± 6.54
67.08 ± 3.9
61.48 ± 4.39
61.6 ± 5.68
ALT (UI/L)70.8 ± 5.01
38.6 ± 3.911
63.86 ± 4.17
52.7 ± 10.42
63.98 ± 11.18

Values represent mean ± standard error of the mean (S.E.P.M), (n = 10). The values were considered significant at ; , ; , vs. vehicle. Analyzed through two-way ANOVA and followed by Bonferroni (n = 10 mice per group).