Hypoglycemic, Hypolipidemic, and Anti-Inflammatory Effects of Beta-Pinene in Diabetic Rats
Table 1
Evaluation of biochemical parameters in rat sera after oral (v.o.) treatment with β-pinene for 7 days.
Parameters
Vehicle —
Glib (5 mg/kg, v.o.)
Beta-pinene (mg/kg, v.o.)
25
50
100
Glucose (mg/dL)
334.1 ± 27.23 —
77.57 ± 21 (76.7%)
393.9 ± 12.21 —
126.3 ± 18.62 (62.2%)
140.4 ± 27.25 (57.9%)
CT (mg/dL)
88.07 ± 8.791 —
65.88 ± 5.721
78.82 ± 6.616 —
86.57 ± 5.694 —
82.17 ± 11.2 —
HDL (mg/dL)
182.6 ± 8.049 —
26.79 ± 6.284 (85.3%)
178.5 ± 18.68 —
64.57 ± 3.867 (64.6%)
46 ± 7.326 (74.8%)
LDL (mg/dL)
64.57 ± 3.867 —
12.93 ± 1.902 (79.9%)
58 ± 7.849 —
15.69 ± 2.948 (75.7%)
14.9 ± 2.241 (76.9%)
VLDL (mg/dL)
112.5 ± 17.31 —
14.72 ± 1.224 (86.9%)
85.82 ± 7.535 (23.7%)
15.92 ± 2.54 (85.8%)
17.08 ± 0.8871 (84.8%)
TG (mg/dL)
354 ± 22.88 —
65.88 ± 5.721 (81.3%)
422 ± 33.73 —
168.4 ± 26.02 (52.7%)
145.6 ± 23.96 (58.8%)
AST (UI/L)
88.68 ± 2.88 —
52.4 ± 6.54
67.08 ± 3.9 —
61.48 ± 4.39 —
61.6 ± 5.68 —
ALT (UI/L)
70.8 ± 5.01 —
38.6 ± 3.911
63.86 ± 4.17 —
52.7 ± 10.42 —
63.98 ± 11.18 —
Values represent mean ± standard error of the mean (S.E.P.M), (n = 10). The values were considered significant at ;,;, vs. vehicle. Analyzed through two-way ANOVA and followed by Bonferroni (n = 10 mice per group).