Salvianolic Acid B Attenuates Iopromide-Induced Renal Tubular Epithelial Cell Injury by Inhibiting the TLR4/NF-κB/NLRP3 Signaling Pathway

Figure 7

Effect of Sal B or TAK-242 in the levels of TLR4, NLRP3, ASC, Caspase-1, p-NF-κB, IL-18, IL-1β, and TNF-α proteins induced by iopromide. (a) Sal B reduced the levels of p-NF-κB, IL-18, IL-1β, and TNF-α n = 3. Data are the mean ± SD. vs. control group; ^#, ^## vs. iopromide group. (b) Sal B decreased the levels of TLR4, NLRP3, ASC, and Caspase-1; n = 3. Data are the mean ± SD. , vs. control group; ^#, ^## vs. iopromide group.

(a)

(b)