Research Article

Edible Bird’s Nest Regulates Hepatic Cholesterol Metabolism through Transcriptional Regulation of Cholesterol Related Genes

Table 2

Food composition, food intake, body weight, and lipid profile.

Animal groupComponent ratio (%)Additional component (%)Food intake (Kcal/kg/day)Initial weight (g)Final weight (g)Chol. (mmol/L)Trig. (mmol/L)LDL (mmol/L)HDL (mmol/L)LDL/HDLTG/HDL

Normal100 : 0 : 0 : 00215.5 ± 33.5a260.4 ± 10.7a384.0 ± 22.9a1.55 ± 0.43a0.62 ± 0.15a0.28 ± 0.11a1.18 ± 0.35a0.24 ± 0.04a0.55 ± 0.15a
HFD65 : 5 : 20 : 100215.0 ± 37.5a262.6 ± 17.7a395.2 ± 16.8a7.47 ± 1.13b1.21 ± 0.38b4.98 ± 1.03b1.05 ± 0.13a4.77 ± 0.98b1.16 ± 0.33b
HFD + SIM65 : 5 : 20 : 10Simvastatin (10 mg/kg)215.7 ± 36.6a267.7 ± 21a375.7 ± 53.4a4.99 ± 1.11c,d0.63 ± 0.18a3.60 ± 1.1b,c1.04 ± 0.17a3.46 ± 0.94b,c0.62 ± 0.22a,b
HFD + EBNL62.5 : 5 : 20 : 102.5% EBN216.1 ± 36.8a261.7 ± 15.4a380.7 ± 25.6a6.04 ± 0.75b,c0.54 ± 0.1a4.52 ± 0.71b,c1.17 ± 0.18a3.94 ± 0.88b,c0.46 ± 0.08a
HFD + EBNH45 : 5 : 20 : 1020% EBN216.5 ± 35.8a257 ± 20.1a368.0 ± 29.3a4.17 ± 1.06d0.44 ± 0.1a2.98 ± 0.83c1.18 ± 0.29a2.63 ± 0.87c0.38 ± 0.08a

EBN: edible bird’s nest. Component ratio: normal pellet% : cholesterol : palm oil : starch. Columns with different letters indicate statistical difference ().