Research Article
Edible Bird’s Nest Regulates Hepatic Cholesterol Metabolism through Transcriptional Regulation of Cholesterol Related Genes
Table 2
Food composition, food intake, body weight, and lipid profile.
| Animal group | Component ratio (%) | Additional component (%) | Food intake (Kcal/kg/day) | Initial weight (g) | Final weight (g) | Chol. (mmol/L) | Trig. (mmol/L) | LDL (mmol/L) | HDL (mmol/L) | LDL/HDL | TG/HDL |
| Normal | 100 : 0 : 0 : 0 | 0 | 215.5 ± 33.5a | 260.4 ± 10.7a | 384.0 ± 22.9a | 1.55 ± 0.43a | 0.62 ± 0.15a | 0.28 ± 0.11a | 1.18 ± 0.35a | 0.24 ± 0.04a | 0.55 ± 0.15a | HFD | 65 : 5 : 20 : 10 | 0 | 215.0 ± 37.5a | 262.6 ± 17.7a | 395.2 ± 16.8a | 7.47 ± 1.13b | 1.21 ± 0.38b | 4.98 ± 1.03b | 1.05 ± 0.13a | 4.77 ± 0.98b | 1.16 ± 0.33b | HFD + SIM | 65 : 5 : 20 : 10 | Simvastatin (10 mg/kg) | 215.7 ± 36.6a | 267.7 ± 21a | 375.7 ± 53.4a | 4.99 ± 1.11c,d | 0.63 ± 0.18a | 3.60 ± 1.1b,c | 1.04 ± 0.17a | 3.46 ± 0.94b,c | 0.62 ± 0.22a,b | HFD + EBNL | 62.5 : 5 : 20 : 10 | 2.5% EBN | 216.1 ± 36.8a | 261.7 ± 15.4a | 380.7 ± 25.6a | 6.04 ± 0.75b,c | 0.54 ± 0.1a | 4.52 ± 0.71b,c | 1.17 ± 0.18a | 3.94 ± 0.88b,c | 0.46 ± 0.08a | HFD + EBNH | 45 : 5 : 20 : 10 | 20% EBN | 216.5 ± 35.8a | 257 ± 20.1a | 368.0 ± 29.3a | 4.17 ± 1.06d | 0.44 ± 0.1a | 2.98 ± 0.83c | 1.18 ± 0.29a | 2.63 ± 0.87c | 0.38 ± 0.08a |
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EBN: edible bird’s nest. Component ratio: normal pellet% : cholesterol : palm oil : starch. Columns with different letters indicate statistical difference ( ). |