Caffeic Acid Prevents Vascular Oxidative Stress and Atherosclerosis against Atherosclerogenic Diet in Rats

Table 2

Effects of caffeic acid (CA) against atherogenic diet- (Ath-) induced alteration(s) in hemodynamic parameters.

Group	AP (mmHg)	HR (BPM)	MAP (mmHg)	SAP (mmHg)	DAP (mmHg)
Control	120.1 ± 2.913	374.2 ± 8.171	120.06 ± 3.28	121.13 ± 4.248	85.5 ± 2.32
Ath control	96.33 ± 2.883^a	449.2 ± 7.977^a	93.36 ± 4.222^a	144.15 ± 4.19^a	99.83 ± 2.822^a
Ath + CA (25 mg/kg)	104.8 ± 2.315^x	403.8 ± 4.512^z	110 ± 3.235^x	134.3 ± 4.006^x	97.5 ± 3.334^x
Ath + CA (50 mg/kg)	112.8 ± 2.496^y	386.7 ± 6.168^z	114.7 ± 3.63^y	129.5 ± 2.754^z	95.17 ± 3.229^y
Control + CA (50 mg/kg)	118.2 ± 5.029	372 ± 3.715	108.2 ± 4.672	121.3 ± 3.989	81.67 ± 1.054^z
Ath + ATORVA (5)	114.67 ± 4.167^z	380.2 ± 4.665^z	119.2 ± 3.26^z	125.3 ± 2.499^z	83.17 ± 1.797^z

Values are expressed as mean ± S.E.M. ^avs. the control group, ^x, ^y, and ^zvs. the Ath control group. Data are analyzed using one-way ANOVA followed by Tukey’s HSD post hoc test. AP : arterial pressure, BPM : beats per minute, HR : heart rate, MAP : mean arterial pressure, SAP : systolic arterial pressure, DAP : diastolic arterial pressure.