Research Article

Caffeic Acid Prevents Vascular Oxidative Stress and Atherosclerosis against Atherosclerogenic Diet in Rats

Table 3

Effects of caffeic acid against atherogenic diet- (Ath-) induced alteration(s) in oxidative stress markers.

GroupMDA (μmol/ml)GSH (nmol/ml)

Control0.499 ± 0.0030.468 ± 0.024
Ath control0.859 ± 0.004a0.133 ± 0.017a
Ath + CA (25 mg/kg)0.738 ± 0.012z0.229 ± 0.013y
Ath + CA (50 mg/kg)0.62 ± 0.006z0.387 ± 0.042z
Control + CA (50 mg/kg)0.503 ± 0.00040.438 ± 0.02
Ath + ATORVA (5)0.515 ± 0.002z0.433 ± 0.004z

Values are expressed as mean ± S.E.M. avs. the control group, y, zvs. the Ath control group. Data are analyzed using one-way ANOVA followed by Tukey’s HSD post hoc test. MDA : malondialdehyde, GSH : glutathione.