Research Article
Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer
Table 2
Details of 14 targets in the core network.
| Number | Uniprot ID | Gene name | Protein name | Degree |
| 1 | P04637 | TP53 | Cellular tumor antigen p53 | 157 | 2 | P31749 | AKT1 | RAC-alpha serine/threonine-protein kinase | 154 | 3 | P15692 | VEGFA | Vascular endothelial growth factor A | 146 | 4 | P05231 | IL6 | Interleukin-6 | 145 | 5 | P01375 | TNF | Tumor necrosis factor | 143 | 6 | P42574 | CASP3 | Caspase-3 | 134 | 7 | P00533 | EGFR | Epidermal growth factor receptor | 132 | 8 | P40763 | STAT3 | Signal transducer and activator of transcription 3 | 130 | 9 | P01584 | IL1B | Interleukin-1 beta | 130 | 10 | P05412 | JUN | Transcription factor AP-1 | 129 | 11 | P01106 | MYC | Myc proto-oncogene protein | 128 | 12 | P03372 | ESR1 | Estrogen receptor | 124 | 13 | P12931 | SRC | Proto-oncogene tyrosine-protein kinase Src | 119 | 14 | P60484 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | 118 |
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