Research Article

Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer

Table 2

Details of 14 targets in the core network.

NumberUniprot IDGene nameProtein nameDegree

1P04637TP53Cellular tumor antigen p53157
2P31749AKT1RAC-alpha serine/threonine-protein kinase154
3P15692VEGFAVascular endothelial growth factor A146
4P05231IL6Interleukin-6145
5P01375TNFTumor necrosis factor143
6P42574CASP3Caspase-3134
7P00533EGFREpidermal growth factor receptor132
8P40763STAT3Signal transducer and activator of transcription 3130
9P01584IL1BInterleukin-1 beta130
10P05412JUNTranscription factor AP-1129
11P01106MYCMyc proto-oncogene protein128
12P03372ESR1Estrogen receptor124
13P12931SRCProto-oncogene tyrosine-protein kinase Src119
14P60484PTENPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN118