Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer

Table 3

Minimum binding energy between the key targets and key ingredients.

Key targets (PDB ID)	Key ingredients	Binding energy (kcal/mol)
TP53 (3TG5)	Quercetin	−8.33
	Kaempferol	−8.05
	Isorhamnetin	−8.72
AKT1 (4EJN)	Quercetin	−7.58
	Kaempferol	−7.39
	Isorhamnetin	−7.12
VEGFA (4QAF)	Quercetin	−6.07
	Kaempferol	−5.95
	Isorhamnetin	−6.53
IL6 (5FUC)	Quercetin	−5.81
	Kaempferol	−5.85
	Isorhamnetin	−5.74
TNF (6X83)	Quercetin	−7.50
	Kaempferol	−7.56
	Isorhamnetin	−7.65
CASP3 (1NME)	Quercetin	−6.85
	Kaempferol	−7.03
	Isorhamnetin	−6.61
EGFR (2RGP)	Quercetin	−7.23
	Kaempferol	−7.25
	Isorhamnetin	−6.74