In Vivo and In Silico Assessment of Diabetes Ameliorating Potentiality and Safety Profile of Gynura procumbens Leaves

Table 4

Overdose toxicity analysis.

Group number	Group status	Treatment specimen	Dose of the treatment specimen (gm/kg)	Group abbreviation
1	Control	Physiological saline	10 mL/kg	C
2	Alloxan + metformin	Alloxan + metformin	150 mg/kg + 5 gm/60 kg	A + M
3	Alloxan + G. procumbens	G. procumbens	150 mg/kg + 25 gm/kg	A + G
4	Metformin	Metformin	5 gm/60 kg	M
5	G. procumbens	G. procumbens	25 gm/kg	G
50 times of lower dose = overdose