Research Article
In Vivo and In Silico Assessment of Diabetes Ameliorating Potentiality and Safety Profile of Gynura procumbens Leaves
Table 9
Binding affinity of natural ligands of G. procumbens with the crystal target alpha-amylase.
| | Compound name | Binding affinity | Class of compounds |
| | Daucosterol | −10.5 | Steroid | | Glucopyranosyl stigmasterol | −9.9 | Steroid | | 1,5-Dicaffeoylquinic acid | −9.6 | Phenol | | 3,5-Dicaffeoylquinic acid | −9.6 | Phenol | | Luteolin | −9.5 | Flavonoid | | Beta-stigmasterol | −9.5 | Steroid | | 3,4-Dicaffeoylquinic acid | −9.4 | Phenol | | Eriocitrin | −9.4 | Flavonoid | | Apigenin | −9.3 | Flavonoid | | Rutin | −9.3 | Flavonoid | | Quercetin | −9.2 | Flavonoid | | Homoorientin | −9.1 | Flavonoid | | Nicotiflorin | −9.1 | Flavonoid | | 5α-Stigmastan-3-one | −9.1 | Steroid | | 4,5-Dicaffeoylquinic acid | −9.1 | Phenol | | Myricetin | −9 | Flavonoid | | 1,4-Dicaffeoylquinic acid | −8.9 | Phenol | | Kaempferol | −8.8 | Flavonoid | | Glucuronide | −8.8 | Phenol | | Negletein | −8.7 | Flavonoid | | Senecivernine | −8.6 | Alkaloid | | Seneciphylline | −8.5 | Alkaloid | | Astragalin | −8.4 | Flavonoid | | Senkirkine | −8.3 | Alkaloid | | Senecionine-N-oxide | −8.3 | Alkaloid | | Erucifoline-N-oxide | −8.1 | Alkaloid | | Retrorsine | −8.1 | Alkaloid | | Neochlorogenic acid | −8 | Phenolic | | Seneciphylline-N-oxide | −8 | Alkaloid | | Chlorogenic acid | −7.9 | Phenol | | Feruloylquinic acid | −7.7 | Phenol | | Acarbose | −7.6 | Reference |
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