Evidence-Based Complementary and Alternative Medicine

Review Article

The Effect and Safety of Xuefu Zhuoyue Prescription for Coronary Heart Disease: An Overview of Systematic Reviews and Meta-Analyses

Table 5

Results of evidence quality. ① The included studies have a large bias in methodology such as randomization, allocation concealment, and blinding. ② The confidence interval overlaps less or the I2 value of the combined results was larger. ③ The sample size from the included studies does not meet the optimal sample size or the 95% confidence interval crosses the invalid line. ④ The funnel chart is asymmetry.
Author, yearOutcomesLimitationsInconsistencyIndirectnessImprecisionPublication biasQuality
Guo−zhong Yi, 2014 [25]RAS00000High
ECG0000−1④Moderate
HDL−C000−1③−1④Low
LDL−C000−1③−1④Low
TG000−1③−1④Low
TC000−1③−1④Low
Shiqi Chen, 2022 [26]LVEF−1①000−1④Low
LVESD−1①000−1④Low
NO−1①00−1③−1④Very Low
ET−1−1①−1②0−1③−1④Very Low
ICAM−1−1①−1②0−1③−1④Very Low
VCAM−1−1①−1②0−1③−1④Very Low
CRP−1①−1②0−1③−1④Very Low
SOD−1①00−1③−1④Very Low
MDA−1①00−1③−1④Very Low
BNP−1①−1②0−1③−1④Very Low
CK−MB−1①−1②0−1③−1④Very Low
Shuo Zhang, 2021 [27]AF0−1②00−1④Low
DAP0−1②00−1④Low
Clinical Efficiency Rate0000−1④Moderate
ECG0000−1④Moderate
WBV000−1③−1④Low
PV0−1②0−1③−1④Very Low
FB0−1②0−1③−1④Very Low
NO000−1③−1④Low
ET−1000−1③−1④Low
AE000−1③−1④Low
Xiaochen Yang, 2014 [28]RAS−1①000−1④Low
ECG−1①00−1③−1④Very Low
Zhou Fang, 2016 [29]Clinical Efficiency Rate−1①−1②000Low
AEECG−1①−1②000Low
Huai Guo, 2017 [30]Clinical Efficiency Rate−1①000−1④Low
CRP−1①−1②0−1③−1④Very Low
ECG−1①000−1④Low
Jinfeng Liu, 2020 [31]RAS−1①0000Moderate
ECG−1①000−1④Low
Min Liu, 2016 [32]Clinical Efficiency Rate (XFZY + CCT vs CT)−1①000−1④Low
Clinical Efficiency Rate (XFZY vs CT)−1①000−1④Low
RAS (XFZY + CCT vs CT)−1①−1②00−1④Very Low
RAS (XFZY vs CT)−1①−1②00−1④Very Low
Yun Liu, 2017 [33]RAS−1①000−1④Low
ECG−1①000−1④Low
Yao Meng, 2021 [34]RAS00000High
ECG0000−1④Moderate
Number of angina attacks0−1②0−1③−1④Very Low
LDL−C0−1②0−1③−1④Very Low
TC0−1②0−1③−1④Very Low
Guohua Zheng, 2012 [35]ECG (XFZY + CT vs CT)−1①000−1④Low
ECG (XFZY vs CT)−1①00−1③−1④Very Low
RAS (XFZY + CCT vs CT)−1①000−1④Low
RAS (XFZY vs CT)−1①00−1③−1④Very Low