Research Article
Effects of the Higenamine, a Potent Compound from Aconitum, on UVB-Induced Photoaging in Hairless Mice
Figure 5
Effect of higenamine on the levels of UVB-induced photoaging in vitro. Cytotoxicity levels measured by MTT (a), and COL1A1 levels measured by ELISA (b) in cells treated with higenamine followed by UVB stimulation. Levels of Smad2 DNA-binding Phosphorylation (c) and COL1A1 (d) in TGF-β siRNA-transfected differentiated human primary fibroblast cells. Values are expressed as the mean ± standard error of the mean. # and ### compared to the control group, , , and compared to the UVB-alone group, & compared to the si-TGF-β group, and @ compared to the higenamine + si-TGF-β + UVB group.
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