Bioactive Components and Potential Mechanism Prediction of Kui Jie Kang against Ulcerative Colitis via Systematic Pharmacology and UPLC-QE-MS Analysis

Figure 6

KJK ameliorates DSS-induced experimental UC. (a) Treatment regimen for all mice groups. (b) Body weight. (c) Changes in disease activity index (DAI) over time. (d) Colon length. (e) Representative images of hematoxylin and eosin stained sections (H & E staining, 200×). (f) Colon length statistics. (g)–(i) Effects of KJK on villi height (VH) and crypt depth (CD) in mice with UC. (j)–(l) Expression of IL-1β, IL-6, and TNF-α proteins in the colon tissues of mice in different treatment groups (n = 8). Measurement data are expressed as mean ± standard error of the mean. One-way analysis of variance (ANOVA) was conducted for the group comparison. , , , compared with the MOD group. ^#, ^##, ^### compared with the CON group.

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