Biejiajian Pill Ameliorates Diabetes-Associated Atherosclerosis through Inhibition of the NLRP3 Inflammasome

Figure 6

BJJ downregulated NF-κB, TXNIP, NLRP3, ASC, caspase-1, and IL-1β protein expression in diabetic ApoE^−/− mouse aortas. (a) NF-κB, TXNIP, NLRP3, ASC, caspase-1, and IL-1β protein expression measured by Western blot in the Con, DM, BJJ-H, BJJ-M, BJJ-L, and ATV groups. (b) NF-κB protein. (c) TXNIP protein. (d) NLRP3 protein. (e) ASC protein. (f) caspase-1 protein. (g) IL-1β protein. , versus the Con group; ^##, ^# versus the DM group; ^▽▽, ^▽ versus the ATV group. Values expressed as mean ± SD (n = 7 per group).

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