[Retracted] Design and In Vitro Evaluation of Novel Cationic Lipids for siRNA Delivery in Breast Cancer Cell Lines

Figure 2

Gel retardation study was carried out using standard gel electrophoresis. (a) Well 1: naked siRNA (50 ng); well 2: C10 : Chol (1 : 1) + siRNA; well 3: C10 : DOTAP (1 : 1) + siRNA; well 4: C10 : DOTAP:Chol (1 : 1:1) + siRNA; well 5: C10 : PEG (1 : 0.5) + siRNA. (b) Well 1: naked siRNA; well 2: C12 : Chol (1 : 1) + siRNA; well 3: C12 : DOTAP:Chol (1 : 1:1) + siRNA; well 4: C12 : DOTAP + siRNA (1 : 1); well 5: C12 : PEG (1 : 0.5) + siRNA. (c). Well 1: naked siRNA; well 2: C14 : Chol (1 : 1) + siRNA; well 3: C14 : DOTAP:Chol (1 : 1:1) + siRNA; well 4: C14 : DOTAP (1 : 1) + siRNA; well 5: C14 : PEG (1 : 0.5) + siRNA.

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(b)

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