[Retracted] Knockdown of lncRNA HOXD-AS2 Improves the Prognosis of Glioma Patients by Inhibiting the Proliferation and Migration of Glioma Cells

Figure 2

Increased HOXD-AS2 expression confers poor prognosis in patients with glioma. (a) The relative expression values of HOXD-AS2/GAPDH in normal brain tissue and grade I, II, III, and IV gliomas were 0.0073 ± 0.0046, 0.0519 ± 0.0514, 1.3477 ± 2.2276, 1.9717 ± 2.9306, and 1.8884 ± 3.1063, respectively, showing significant differences between the normal brain tissue and tumor tissues of different grades (). (b) The Kaplan–Meier overall survival curves according to HOXD-AS2 expression level. Glioma patients with high HOXD-AS2 expression had significantly shorter median survival than patients with low HOXD-AS2 expression (). (c, d) Low HOXD-AS2 expression was significantly associated with longer median survival in patients with low-grade glioma () but not in patients with high-grade glioma. NB, normal brain tissue; I–IV, I–IV glioma. .

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