Curcumin-Based Inhibitors of Thrombosis and Cancer Metastasis Promoting Factor CLEC 2 from Traditional Medicinal Species Curcuma longa

Table 1

Pharmacokinetic properties.

Properties	Bisdemethoxycurcumin	Demethoxycurcumin	Dihydrocurcumin	Piperine
MW	291.0	319.97	347.97	256.99
Log P	1.887	2.024	1.694	2.518
Log P	1.519	1.154	0.258	−0.635
HBA	4	5	6	4
HBD	0	0	0	0
TPSA	34.14	26.3	52.6	38.77
AMR	98.41	107.08	110.87	82.03
nRB	6	6	9	4
nAtom	23	25	27	21
RC	2	2	2	3
nRigidB	18	20	19	19
nAromRing	2	2	2	1
Nhb	4	5	6	4