Gualou Guizhi Decoction Improves Glucose Metabolism and Alleviates Microglia-Associated Inflammation after Cerebral Ischemia

Figure 3

The effects of GL treatment on Glut-1 expression and the hallmarks of microglia and astrocytes after cerebral ischemia/reperfusion. Images were captured on the adjacent region of the ischemic area. Integrated density data were obtained from 5 animals in each group. (a) Glut-1, (b) Iba-1, (c) GFAP, and (d) quantification of integrated density of Glut-1, Iba-1, and GFAP. Sham: sham-operated rats, M + Veh: MCAO rats treated with vehicle, and M + GL: MCAO rats intragastrically administered with GL. Results were presented as means ± SE. ^# and ^##, M + Veh group compared with the Sham group; and , M + GL group compared with the M + Veh group; ^ΔΔ, M + GL group compared with the sham group. Bar in (a) and (b): 75 μm and bar in (c): 100 μm.

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