Research Article
Analysis of Medication Rule of Primary Epilepsy Based on Xiaocheng Yan’s Clinical Experience Collection of Epilepsy
Table 3
Mechanism of action of antiepileptic allopathic drugs.
| No. | Category | Drugs | Mechanism of action | Side effects | References |
| 1 | Iminostilbene | Carbamazepine and oxcarbazepine | Inhibition of neuronal Na + currents | Bone marrow suppression, skin rash, and visual disturbances | (Ambrósio et al.) [16] | 2 | Benzodiazepine | Clonazepam | Agonist action at the GABAA receptor | Drowsiness, cognitive impairment, and euphoria | (Campo-Soria et al.) [17] | 3 | Aliphatic carboxylic acid | Valproic acid | Increases the synthesis of GABA | Blurred vision, hair loss, change in appetite, and constipation | (Rosenberg) [18] | 4 | | Levetiracetam | It modulates synaptic neurotransmitter release through binding to the synaptic vesicle protein SV2A in the brain | Vomiting, tiredness, throat irritation, headache, diarrhea, and cough | (Noachtar et al.) [19] | 5 | | Topiramate | It inhibits the AMPA subtype glutamate receptor and blocks Na + channels. It also increases GABA activity at GABA receptors | Dizziness, somnolence, diarrhea, depression, and nystagmus | (Kenna et al.) [20] |
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