Antitoxic Effects of Curcumin against Obesity-Induced Multi-Organs’ Biochemical and Histopathological Abnormalities in an Animal Model

Figure 5

Histopathological findings of liver, duodenum and heart of various study groups. (a–c): Photomicrographs of male albino rat’s liver stained with haematoxylin and eosin (HE). (×200 = 100 μm). (a): Liver photomicrograph of the CD group. (b): Liver photomicrograph of the HFD group. (c): Liver photomicrograph of the HFDC group. Central vein (CV), hepatocytes (h), blood sinusoids (arrowhead), congested central vein (Con), macrovesicular steatosis (), and microvesicular steatosis (thin arrow). (d–f): Photomicrographs of male albino rat’s duodenum stained with haematoxylin and eosin (HE). (×200 = 100 μm). (d): Duodenal photomicrograph of the CD group. (e): Duodenal photomicrograph of the HFD group. (f): Duodenal photomicrograph of the HFDC group. Musculosa (M), Brunner’s glands (B), Lamina propria (L), simple columnar epithelium of villus (thin arrow), Goblet cells (arrow head), epithelial erosion (thick arrow), inflammatory infiltration (I), Necrosis (double arrow) of the inner circular muscle fibers of musculosa, Massive amounts of adipose tissues (stars). (g–i): Photomicrographs of male albino rat’s heart stained with haematoxylin and eosin (HE). (×400 = 50 μm). (a): Heart photomicrograph of the CD group. (b): Heart photomicrograph of the HFD group. (c): Heart photomicrograph of the HFDC group. Muscle fibers (MC), the intercellular spaces (S), vesicular nuclei (arrow), intercalated discs (I) (arrow head), damage of cardiac muscle fibers (), inflammatory cells (double arrows), separation of cardiac muscle fibers (stars), and extravasated red blood cells (thin arrow).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)