Exploring the Mechanism through which Phyllanthus emblica L. Extract Exerts Protective Effects against Acute Gouty Arthritis: A Network Pharmacology Study and Experimental Validation
Table 3
Degree value analysis of pathways in CTP network.
Pathways
Betweenness centrality
Closeness centrality
Degree
HIF-1 signaling pathway
0.10670956
0.44099379
15
PI3K-akt signaling pathway
0.06644801
0.4251497
12
TNF signaling pathway
0.13508328
0.42011834
11
Ras signaling pathway
0.03548477
0.41520468
11
Rap1 signaling pathway
0.03281526
0.41040462
11
Nonalcoholic fatty liver disease
0.09957878
0.41040462
10
Insulin resistance
0.08416535
0.40571429
10
Focal adhesion
0.02776726
0.40112994
10
Chemokine signaling pathway
0.06689398
0.41040462
10
Toll-like receptor signaling pathway
0.04355976
0.40571429
9
T-cell receptor signaling pathway
0.04668759
0.40112994
8
Osteoclast differentiation
0.0411098
0.39664804
8
FoxO signaling pathway
0.01449155
0.39226519
8
NOD-like receptor signaling pathway
0.03845429
0.37566138
7
NF-kappaB signaling pathway
0.02278709
0.38378378
7
Neurotrophin signaling pathway
0.01906849
0.38797814
7
MAPK signaling pathway
0.01459004
0.38797814
7
ErbB signaling pathway
0.01213661
0.38378378
7
Epithelial cell signaling in helicobacter pylori infection
