Intervention Effects of Okra Extract on Brain-Gut Peptides and Intestinal Microorganisms in Sleep Deprivation Rats

Figure 3

OE improved depressive behaviors and mitigated stress and inflammatory responses in SD rats. Rats were subjected to SD along with intragastric administration. (a) Assessment of body weight; (b) statistics of average daily water consumption; (c)–(e) assessment of OFT scores; (f) determination of sucrose preference rate; (g)-(h) measurement of NE and MT levels in serum; (i)–(m) ELISA determined the levels of inflammatory factors (IL-1β, IL-6, TNF-α, IL-4, and IL-10). N = 8, data were expressed as mean ± standard deviation. One-way ANOVA was used for comparisons among multiple groups, followed by Tukey’s test. Compared with the SD group, , , ; compared with the L-OE + SD group, ^#, ^##.

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