Evaluation of a Polyherbal Formulation on the Management of Migraine Headaches due to Functional Dyspepsia: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

Table 5

Some reported gastrointestinal actions of the polyherbal formulation ingredients.

Ingredients	Scientific name	Important phytochemical	Actions on GI
Damask	Rosa damascena	Geraniol, citronellol, nerol, phenylethyl alcohol [76].	Laxative, astringent [77] increases the lower oesophageal sphincter tonicity and anti-reflux [64,78].
Coriander	Coriandrum sativum	Linalool, α-pinene, limonene, gamma-terpinene, camphor, geraniol, geranylacetate [79].	Carminative, improving gastric juices secretion, spasmolytic. Approved for dyspeptic complaints, Loss of appetite and complaints of the upper abdomen [65,80,81].
Ginger	Zingiber officinalis	Zingiberone, curcumene, bisrabolone, α-pinene, β-pinene, limonene, p-cymene, α-terpineol, and verticiole [82,83].	Prokinetic, antiulcer, carminative, anti-dyspeptic, Useful for nausea relief, decrease pressure on the lower oesophagal sphincter, reduce intestinal cramping, and stimulate antral contractions in healthy people individuals and gastrotonic [63,67,83].
Indian gooseberry	Phyllantus embelica	Phyllantadine, ascorbic acid, seasamine, beta carotene, estradiol, astagallin, lupenol, kaemferole, phyllanthine, chebulanin [84–87].	It increases the lower esophagal sphincter tonicity, anti-reflux, prokinetic and laxative activities, gastrotonic [41,88–90].