Research Article

Gynostemma Glycosides Protect Retinal Ganglion Cells in Rats with Chronic High Intraocular Pressure by Regulating the STAT3/JAK2 Signaling Pathway and Inhibiting Astrocyte and Microglia Activation

Table 1

Comparison of IOP before and after modeling in each group of rats (mean ± SD, n = 10).

GroupIOP (mmHg)
Before molding30 minutes after mold making1 week after mold making2 weeks after mold making

A13.43 ± 0.9913.34 ± 0.7413.78 ± 0.7414.05 ± 1.06
B13.30 ± 0.8632.04 ± 4.42ab31.86 ± 4.42ab33.53 ± 3.20ab
C13.30 ± 0.8234.42 ± 4.94ab30.57 ± 4.94ab35.71 ± 2.61ab
D13.30 ± 0.9034.46 ± 3.17ab31.72 ± 3.17ab36.64 ± 2.64ab
E13.54 ± 0.9033.12 ± 4.44ab32.61 ± 4.44ab36.09 ± 2.68ab
F13.30 ± 0.9432.01 ± 3.45ab31.77 ± 3.35ab32.19 ± 2.42ab

Notes: A: the blank group; B: negative control group; C: gynostemma glycosides low-dose group; D: gynostemma glycosides medium-dose group; E: gynostemma glycosides high-dose group; F: positive control group. Compared with group A, a. Comparison with the same group before modeling, b.