Research Article

Gynostemma Glycosides Protect Retinal Ganglion Cells in Rats with Chronic High Intraocular Pressure by Regulating the STAT3/JAK2 Signaling Pathway and Inhibiting Astrocyte and Microglia Activation

Table 4

Relative expression of STAT3 and JAK2 mRNA (mean ± SD, n = 10).

GroupSTAT3 mRNAJAK2 mRNA

A0.91 ± 0.13a0.93 ± 0.11a
B6.65 ± 0.887.89 ± 0.35
C4.66 ± 0.53a5.62 ± 0.71a
D3.15 ± 0.18ab3.26 ± 0.23ab
E1.71 ± 0.09abc1.88 ± 0.19abc
F4.67 ± 0.32a5.69 ± 0.77a

Notes: A: the blank group; B: negative control group; C: gynostemma glycosides low-dose group; D: gynostemma glycosides medium-dose group; E: gynostemma glycosides high-dose group; F: positive control group. Compared with group B, a. Compared with group F, b. Compared with group D, c.