Research Article

Gynostemma Glycosides Protect Retinal Ganglion Cells in Rats with Chronic High Intraocular Pressure by Regulating the STAT3/JAK2 Signaling Pathway and Inhibiting Astrocyte and Microglia Activation

Table 5

Electrophoresis diagrams of JAK2, P-JAK2, STAT3, and P-STAT3 protein expression of rats in each group (mean ± SD, n = 10).

GroupSTAT3JAK2P-STAT3P-JAK2

A0.91 ± 0.11a0.93 ± 0.11a3.45 ± 2.38a12.61 ± 3.42a
B6.65 ± 0.887.89 ± 0.3536.15 ± 4.9140.76 ± 4.93
C4.66 ± 0.53a5.62 ± 0.71a31.13 ± 3.48a33.29 ± 5.79a
D3.15 ± 0.18ab3.26 ± 0.23ab24.54 ± 4.36ab28.39 ± 7.56a
E1.71 ± 0.09abc1.88 ± 0.19abc15.62 ± 6.12abc24.49 ± 8.49a
F4.67 ± 0.32a5.69 ± 0.77a33.73 ± 5.42a35.39 ± 6.12a

Notes: A: the blank group; B: negative control group; C: gynostemma glycosides low-dose group; D: gynostemma glycosides medium-dose group; E: gynostemma glycosides high-dose group; F: positive control group. Compared with group B, a. Compared with group F, b. Compared with group D, c.