Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation

Figure 10

Experimental design. (A) 20 Wistar rats (10 control group; 10 hydroethanolic extract of flowers of the A. oleracea-treated group). (B) 20 SHR (10 control group, 10 hydroethanolic extract of A. oleracea flowers-treated group group. (C) Hydroethanolic extract of A. oleracea flowers administration via gavage. Timeline with the order analysis: collection, identification, and preparation of the A. oleracea extract, oral bioavailability, weekly weighing, pressure measurement, metabolic cage, euthanasia, biochemical analysis, histological analysis, in silico evaluation, and statistical analysis.