Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation

Figure 3

Weight assessment of the animals submitted to treatment via gavage with the hydroethanolic extract of flowers of A. oleracea; WC = control Wistar, WT = treated Wistar, SHRC = control spontaneously hypertensive rats, SHRT = treated spontaneously hypertensive rats where controls were treated with 100 μL of saline, and those treated with 100 mg/kg of EHFAo. Data are expressed as the mean ± standard deviation (SD) of the control and treated groups. Statistical analysis was performed using one-way ANOVA followed by Sidak’s multiple comparison test when compared to controls.