Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation

Figure 5

Systolic blood pressure values of rats of all strains in the group were measured weekly by tail plethysmography. Data were expressed as mean ± standard error of the mean. WC = Wistar control, WT = treated Wistar, SHRC = spontaneously hypertensive rat control, and SHRT = treated spontaneously hypertensive rat. WC and SHRC = 100 μL saline; WT and SHRT = 100 mg/kg EHFAO. Statistical analysis of variance; two-way ANOVA followed by multiple comparisons using GraphPad Prism 6.0. , when the group was compared with the WC group.