Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation

Table 1

Qualitative and quantitative analysis of the EHFAO. Data were obtained by HPLC-ESI-QTOF-MS/MS identifying spilanthol (N-isobutyl amide-2E, 6Z, and 8E-decatrienoic acid) as the major constituent at a retention time of 6.97 minutes.

Overall yield (%)	Compound	Retention (min)	Standard m/z	m Sigma	Content (%)	Concentration over ppm ± SD
1.82	Spilanthol	6.97	222.1847	0.75	97.7	50 ± 15

m/z: charge/mass ratio; min: minutes; SD: standard deviation. Source: author.