Pharmacological Characteristics of the Hydroethanolic Extract of Acmella oleracea (L) R. K. Jansen Flowers: ADME/Tox In Silico and In Vivo Antihypertensive and Chronic Toxicity Evaluation

Table 2

Oral bioavailability properties and application of the Lipinski rule for the phytochemicals found in the hydroethanolic extract of flowers of A. oleracea.

Compounds	LogP^2	MW^1	HBA^3	HBD^4	Smiles code^5
Spilanthol	3.39	221.34	1	1	CC=CC=CCCC=CC(=O)NCC(C)C
D-limonen	2.72	136.23	0	0	CC1=CCC(CC1)C(=C)C
Scopoletin	1.86	192.17	4	1	COC1=C(C=C2C(=C1)C=CC(=O)O2)O

¹Molecular weight, ²logarithm of the partition between of n-octanol and water phases, ³hydrogen bond acceptor, ⁴hydrogen bond donor, and ⁵Smiles code obtained in PubChem.