Evidence-Based Complementary and Alternative Medicine

Research Article

Decompression Mechanism of Radish Seed in Prehypertension Rats through Integration of Transcriptomics and Metabolomics Methods

Table 2

Differentially expressed genes in response to RS.


Gene ID	Gene name	Gene description	PHT vs C			R vs PHT
Gene ID	Gene name	Gene description	Log₂FC		Trend	Log₂FC		Trend

ENSRNOG00000021027	Dbp	D-box binding PAR bZIP transcription factor	3.567303898	4.30E − 33	Up	−3.264046382	7.90E − 25	Down
ENSRNOG00000046202	Metrnl	Meteorin-like, glial cell differentiation regulator	1.969308729	2.56E − 11	Up	−1.34813636	9.33E − 05	Down
ENSRNOG00000027722	H1fx	H1 histone family, member X	1.851322912	1.01E − 07	Up	−1.394696117	0.031399605	Down
ENSRNOG00000008862	Abcg4	ATP binding cassette subfamily G member 4	1.655409762	2.47E − 06	Up	−1.956800064	1.68E − 05	Down
ENSRNOG00000021183	LOC102552640	REST corepressor 2-like	1.716720712	1.59E − 05	Up	−1.588589807	0.000560329	Down
ENSRNOG00000045797	Lep	Leptin	1.947370701	4.43E − 05	Up	−2.081133473	0.000226691	Down
ENSRNOG00000012172	Spi1	Spi-1proto-oncogene	1.321833554	0.000127507	Up	−1.03255045	0.026766336	Down
ENSRNOG00000020030	Crlf1	Cytokine receptor-like factor 1	1.004675242	0.000150727	Up	−1.489669973	0.00030577	Down
ENSRNOG00000021041	Fam171a2	Family with sequence similarity 171, member A2	1.107709992	0.000154887	Up	−1.164578955	0.004227803	Down
novel.1017	—	PF00249: Myb-likeDNA-binding domain	1.763815781	0.000331296	Up	−1.607636495	0.018048572	Down
ENSRNOG00000058006	Sncg	Synuclein, gamma	1.260680962	0.000372941	Up	−1.667606306	0.001152749	Down
ENSRNOG00000024923	Nnat	Neuronatin	1.025714286	0.000425846	Up	−2.187827367	6.74E − 08	Down
ENSRNOG00000017463	Bloc1s3	Biogenesis of lysosomal organelles complex-1, subunit 3	1.734624953	0.000454039	Up	−1.014924909	0.036667207	Down
ENSRNOG00000008536	Actc1	Actin, alpha, cardiac muscle 1	2.041299184	0.000480238	Up	−3.909775367	1.13E − 08	Down
ENSRNOG00000048961	Bhlhe41	Basic helix-loop-helix family, member e41	1.714013346	0.000532216	Up	−1.459316165	0.027634003	Down
ENSRNOG00000010575	Dapp1	Dual adaptor of phosphotyrosine and 3-phosphoinositides 1	1.140266497	0.001212619	Up	−1.100294229	0.033236941	Down
ENSRNOG00000018735	Cd74	CD74 molecule	1.112172854	0.001238105	Up	−1.05684107	0.045825102	Down
ENSRNOG00000032844	RT1-Da	RT1 class II, locus Da	1.261046152	0.001903907	Up	−1.213526605	0.020265998	Down
ENSRNOG00000018740	Ugt1a1	UDP glucuronosyltransferase family 1 member A1	1.058435351	0.00383177	Up	−1.155931747	0.001591236	Down
ENSRNOG00000032639	Foxo6	Forkhead box O6	1.849242891	0.003855283	Up	−2.270257913	0.001325659	Down
ENSRNOG00000011478	Ackr4	Atypical chemokine receptor 4	1.107026643	0.006340248	Up	−1.53929622	0.001046107	Down
ENSRNOG00000019330	Procr	Protein C receptor	1.022734389	0.006435929	Up	−1.086629096	0.015518083	Down
ENSRNOG00000003144	Gprc5c	G protein-coupled receptor, class C, group 5, member C	1.132504804	0.006805995	Up	−1.429058886	0.005581253	Down
ENSRNOG00000000451	RT1-Ba	RT1 class II, locus Ba	2.226046253	0.007035112	Up	−2.588878749	0.002146712	Down
ENSRNOG00000046560	AC109096.1	—	1.075351448	0.009966035	Up	−1.011598656	0.036021456	Down
ENSRNOG00000055564	RGD1564664	Similar to LOC387763 protein	1.294671413	0.015607613	Up	−1.711461574	0.032923765	Down
ENSRNOG00000003348	Rasd1	Ras-related dexamethasone induced 1	1.16515603	0.016140158	Up	−1.364279536	0.04658816	Down
ENSRNOG00000061998	AABR07044421.1	—	1.681819659	0.01966356	Up	−3.988901029	1.55E − 06	Down
ENSRNOG00000020129	Cdh3	Cadherin 3	1.574152395	0.025609303	Up	−2.943616786	0.001152749	Down
ENSRNOG00000052070	Aldh1a3	Aldehyde dehydrogenase 1 family, member A3	1.049569581	0.033518518	Up	−1.348015788	0.013982309	Down
ENSRNOG00000017786	Acta1	Actin, alpha 1, skeletal muscle	1.400082213	0.036004573	Up	−2.147189191	0.049136448	Down
ENSRNOG00000029980	Zbtb16	Zinc finger and BTB domain containing 16	−4.106676387	4.01E − 28	Down	3.244177922	3.38E − 10	Up
ENSRNOG00000003669	Myocd	Myocardin	−2.866059593	6.36E − 11	Down	2.101360276	1.55E − 06	Up
ENSRNOG00000007029	Dnaja1	DnaJ heat shock protein family (Hsp40) member A1	−2.220517729	3.65E − 10	Down	1.610706495	1.55E − 06	Up
ENSRNOG00000026643	Chordc1	Cysteine and histidine rich domain containing 1	−1.60790284	4.43E − 05	Down	1.359311638	4.13E − 06	Up
ENSRNOG00000003666	Jchain	Immunoglobulin joining chain	−1.932062043	0.03948545	Down	2.75879606	1.40E − 05	Up
ENSRNOG00000017864	Bdp1	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	−1.407811425	2.14E − 08	Down	1.305094452	0.000312668	Up
ENSRNOG00000014248	Erbb4	Erb-b2 receptor tyrosine kinase 4	−2.289119562	4.43E − 05	Down	2.399656764	0.001152749	Up
ENSRNOG00000014509	Sacs	Sacsin molecular chaperone	−1.547973674	5.71E − 08	Down	1.116175993	0.001325659	Up
novel.811	—	—	−2.332034287	0.000225106	Down	2.543235677	0.001532242	Up
ENSRNOG00000011358	Hipk3	Homeodomain-interacting protein kinase 3	−1.03711145	0.000286261	Down	1.157986776	0.006627494	Up
ENSRNOG00000021525	Nbeal1	Neurobeachin-like 1	−1.132308326	0.000246838	Down	1.136606099	0.007849647	Up
ENSRNOG00000013587	Fam135a	Family with sequence similarity 135, member A	−1.641150683	1.30E − 09	Down	1.371986259	0.008457281	Up
ENSRNOG00000007706	Prkaa2	Protein kinase AMP-activated catalytic subunit alpha 2	−1.344153744	1.07E − 06	Down	1.197473792	0.010909631	Up
ENSRNOG00000061862	Zbtb10	Zinc finger and BTB domain containing 10	−1.496108262	1.89E − 06	Down	1.151806982	0.015116305	Up
ENSRNOG00000014448	Arntl	Aryl hydrocarbon receptor nuclear translocator-like	−1.57376632	2.47E − 06	Down	1.304448787	0.017388842	Up
ENSRNOG00000056135	Tsc22d3	TSC22 domain family, member 3	−1.122847202	4.32E − 07	Down	1.111465323	0.017814725	Up
ENSRNOG00000005957	Slc4a7	Solute carrier family 4 member 7	−1.091006955	0.013775843	Down	1.352856498	0.023295922	Up
ENSRNOG00000034269	Ago3	Argonaute RISC catalytic component 3	−1.280325929	0.005014064	Down	1.291240162	0.025121895	Up
ENSRNOG00000010065	Dgkh	Diacylglycerol kinase, eta	−1.955551832	0.000127205	Down	1.637806704	0.025121895	Up
ENSRNOG00000056716	Zbtb20	Zinc finger and BTB domain containing 20	−1.975779905	6.49E − 05	Down	1.636603951	0.026446922	Up
ENSRNOG00000003742	Cdkl5	Cyclin-dependentkinase-like 5	−1.88256747	1.15E − 11	Down	1.371912691	0.027923496	Up
ENSRNOG00000020479	Pik3c2a	Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	−1.114519009	5.97E − 06	Down	1.008209449	0.031399605	Up
ENSRNOG00000034066	Hspa8	Heat shock protein family A (Hsp70) member 8	−1.07279022	0.003973704	Down	1.003978216	0.032923765	Up
ENSRNOG00000011619	Myo9a	Myosin IXA	−1.08677208	0.000331296	Down	1.010547893	0.033236941	Up
ENSRNOG00000013884	Psd3	Pleckstrin and Sec7 domain containing 3	−1.386129469	0.004016511	Down	1.325924895	0.037676589	Up
novel.55	—	—	−1.234762995	5.91E − 06	Down	1.037997999	0.040884285	Up
ENSRNOG00000042519	Peak1	Pseudopodium-enriched atypical kinase-1	−1.121812695	0.005693797	Down	1.274772342	0.043162444	Up
ENSRNOG00000018804	Ripor2	RHO family-interacting cell polarization regulator 2	−1.624879022	9.28E − 06	Down	1.141179168	0.045191834	Up
ENSRNOG00000010640	Agtr1b	Angiotensin II receptor, type 1b	−2.329759002	2.24E − 06	Down	1.702703791	0.04658816	Up
ENSRNOG00000014037	Dcun1d3	Defective in cullin neddylation 1 domain containing 3	−1.063960359	0.007204179	Down	1.083854353	0.046969316	Up
ENSRNOG00000054515	Fgd6	FYVE, RhoGEF, and PH domain containing 6	−1.180943279	0.013459939	Down	1.413119049	0.048490736	Up
ENSRNOG00000042679	AABR07006860.1	Ligand-dependent nuclear receptor corepressor	−1.050601726	0.015762342	Down	1.209207063	0.048490736	Up
ENSRNOG00000045863	Naa16	N (alpha)-acetyltransferase 16, NatA auxiliary subunit	−1.006785492	0.030931715	Down	1.086757495	0.048490736	Up
ENSRNOG00000031092	Rock1	Rho-associatedcoiled-coil containing protein kinase-1	−1.410378076	0.001917703	Down	1.529559464	0.049136448	Up